Thyroid Stimulating Hormone Receptor Antibody (TRAb) 編輯

Clinical Significance: 編輯

  1. differential diagnosis of Graves disease versus toxic nodular goiter.
  2. aids in the diagnosis of Graves disease (positive in greater than 85%)
  3. to monitor the efficacy of anti-thyroid drug therapy to predict the likelihood of disease remission.
    1. a high positive titer: irradiation of the thyroid gland
    2. a lower antibody titers: given anti-thyroid medication

Reference Interval: 編輯

Reported as percent inhibition of TSH binding:

  • <10% = Negative
  • 10-15% = Indeterminate
  • >15% = Positive

Reference 編輯

  1. Thyroid Stimulating Hormone Receptor Antibody (TRAb), ARUP's Guide to Clinical Laboratory Testing